Interaction network and enrichment analysis of genes upregulated in MAT1A KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00039228
TitleInteraction network and enrichment analysis of genes upregulated in MAT1A KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between MAT1A KO cells and control cells in the Liver tumoral tissue (having hepatocellular carcinoma) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Cyp2a5|Spp1|Igfbp1|E430024C06Rik|Gm3776|Glul|Cyp4a12a|H19|Rplp0|Blvrb|Gstm3|Actg1|Tff3|Apoc2|Nme2|Krt18|Rpl19|Apoa4|Sult1a1|Rpl17-ps10|Gpx4|Lect2|Ces2d-ps|Lgals1|Creg1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2941
Cell TypeLiver tumoral tissue (having hepatocellular carcinoma)
Gene Symbol (human)MAT1A
Gene Symbol (mouse)Mat1a
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1539797, GSM1539798, GSM1539799, GSM1539800, GSM1539801
Perturbed SamplesGSM1539807, GSM1539808, GSM1539809, GSM1539810, GSM1539811
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE63062
Gene Expression Omnibus
Expression data from GNMT and MAT1A knockout models that develop all the stages of non-alcoholic fatty liver disease including hepatocellular carcinom...
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.