Interaction network and enrichment analysis of genes downregulated in MIR210 OE
Canned Analysis
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General Information
AccessionDCA00039265
TitleInteraction network and enrichment analysis of genes downregulated in MIR210 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MIR210 OE cells and control cells in the Human Umbilical Vein Endothelial Cells (HUVEC) infected by retroviral vectors bearing a control scramble or pre-miR-210 sequence cell type.
Analysis URLhttp://genemania.org/#/search/human/HSP90AA1|SLC38A2|LDHB|BZW1|EIF3E|PLS3|GJA1|HIF1A|UAP1|DDX21|SRP9|NPM1|RAI14|PLOD2|RPL36AL|RAP1B|ITGAV|HMGB1|HNRNPA1P10|DHX15|SDCBP|DEK|RND3|WBP5|COX2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2971
Cell TypeHuman Umbilical Vein Endothelial Cells (HUVEC) infected by retroviral vectors bearing a control scramble or pre-miR-210 sequence
Gene Symbol (human)MIR210
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM424759, GSM424760, GSM424761
Perturbed SamplesGSM424762, GSM424763, GSM424764
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE16962
Gene Expression Omnibus
Effect of mir-210 overexpression or down-modulation on human umbilical vein cells
14
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