Interaction network and enrichment analysis of genes downregulated in IKBKB expression of a constitutively active allele of the IÎ&ord

General Information

Accession	DCA00039271
Title	Interaction network and enrichment analysis of genes downregulated in IKBKB expression of a constitutively active allele of the IÎ&ord
Description	The analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between IKBKB expression of a constitutively active allele of the IÎ&ord cells and control cells in the Ramos cells; cell type: human Burkitt lymphoma; dsmz no.: ACC 603 origin: established from the ascitic fluid of a 3-year-old boy with American-type Burkitt lymphoma in 1972; cells were described to be EBV-negative but EBV infectible, to carry the (8;14) translocation and p53 mutations cell type.
Analysis URL	http://genemania.org/#/search/human/IGJ\|TCL1A\|TOP2B\|HMGB1\|IGLL1\|KIAA0226L\|CCNB1IP1\|VPREB1\|RPS25\|CKS1B\|HNRNPA1P10\|OAZ1\|ID3\|EIF3E\|TRAM1\|CCL4\|TUBA1A\|CXCR4\|CD81\|HIST1H4C\|RPL36A\|FAM72A\|RCSD1\|HMGN2\|SRP9
Upload Date	September 20, 2017
Uploader	maayanlab

Metadata

Analysis Curator	gszeto
CREEDS ID	gene:2974
Cell Type	Ramos cells; cell type: human Burkitt lymphoma; dsmz no.: ACC 603 origin: established from the ascitic fluid of a 3-year-old boy with American-type Burkitt lymphoma in 1972; cells were described to be EBV-negative but EBV infectible, to carry the (8;14) t
Gene Symbol (human)	IKBKB
Gene Symbol (mouse)	Ikbkb
Organism	human
Perturbation Type	expression of a constitutively active allele of the IÎ&ord