Interaction network and enrichment analysis of genes upregulated in TCF3 Deficiency
Canned Analysis
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General Information
AccessionDCA00039286
TitleInteraction network and enrichment analysis of genes upregulated in TCF3 Deficiency
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between TCF3 Deficiency cells and control cells in the DN2 thymocyte cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Tmsb4x|Hba-a2|Hbb-bs|Ifitm1|Actg1|Lgals1|Nme2|Kxd1|Rps2-ps6|LOC100048117|Rps2|Rplp0|Gm1821|H2-L|Rps6-ps4|Tuba1a|Rplp1|Ptma|Tuba1b|Ino80|Zfp526|Rps14|Eef1a1|Rpl3|Rpl10a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:298
Cell TypeDN2 thymocyte
Gene Symbol (human)TCF3
Gene Symbol (mouse)Tcf3
Organismmouse
Perturbation TypeDeficiency
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1058959, GSM1058960, GSM1058961
Perturbed SamplesGSM1058962, GSM1058963, GSM1058964
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE43224
Gene Expression Omnibus
E2A transcription factor deficiency effect on DN2 thymocyte
7
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