Interaction network and enrichment analysis of genes downregulated in INHA KO
Canned Analysis
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General Information
AccessionDCA00039303
TitleInteraction network and enrichment analysis of genes downregulated in INHA KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between INHA KO cells and control cells in the Preovulatory granulosa cell cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Inha|Tulp2|Lrp11|Hsd17b2|Fam162b|Gstm6|Nr0b1|Coch|Tmprss13|Gpr155|Pik3ip1|Atp4b|Itih2|Fgd5|Comp|Mug2|Nckap5|Bmp2|Asb4|Ccbl2|Mro|Dmkn|Tnfsf11|Ntn4|Cadps
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDgene:2993
Cell TypePreovulatory granulosa cell
Gene Symbol (human)INHA
Gene Symbol (mouse)Inha
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM513621, GSM513622, GSM513623
Perturbed SamplesGSM513624, GSM513625, GSM513626
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20466
Gene Expression Omnibus
Comparison of granulosa cells from WT and Inha KO mice following gonadotropin stimulation
7
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