Interaction network and enrichment analysis of genes downregulated in HNF1A KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00039307
TitleInteraction network and enrichment analysis of genes downregulated in HNF1A KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between HNF1A KO cells and control cells in the Jejunum cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Fabp1|Guca2b|Lct|Spink3|Apoa4|Cyp3a11|Guca2a|Apoc2|Cyp2d26|Anxa13|Glud1|Ggt1|Cyp3a25|Anpep|Aoc1|Cubn|Reg3a|Arg2|Slc5a4b|Amn|Akr1c12|Ugt2b34|Slc6a20a|Slc25a45|Cndp2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDgene:2995
Cell TypeJejunum
Gene Symbol (human)HNF1A
Gene Symbol (mouse)Hnf1a
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM568585, GSM568586, GSM568620
Perturbed SamplesGSM568514, GSM568515, GSM568516
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23040
Gene Expression Omnibus
Loss of Hepatocyte-Nuclear-Factor-1 Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.