Interaction network and enrichment analysis of genes upregulated in GFI1B KO
Canned Analysis
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General Information
AccessionDCA00039342
TitleInteraction network and enrichment analysis of genes upregulated in GFI1B KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between GFI1B KO cells and control cells in the Hematopoietic stem cells (Cd150+, Cd48-, Lin-, Sca+, c-kit+) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Plek|Pf4|Rap1b|Slc14a1|Gfi1b|Cdk6|Lgals1|Pbx1|Fyb|Itgb3|Rsu1|Dhrs3|Timp3|Nupr1|Xist|Vezf1|Plxnc1|Pdcd4|Trpc6|Kctd1|Iqgap2|Clec1b|Nkg7|Mfsd2b|Txnip
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJuliana
CREEDS IDgene:3013
Cell TypeHematopoietic stem cells (Cd150+, Cd48-, Lin-, Sca+, c-kit+)
Gene Symbol (human)GFI1B
Gene Symbol (mouse)Gfi1b
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM518397, GSM518398, GSM518399
Perturbed SamplesGSM518400, GSM518401, GSM518402
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20655
Gene Expression Omnibus
Effect of loss of Gfi1b on hematopietic stem cells
7
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