Interaction network and enrichment analysis of genes upregulated in TMEM100 KO
Canned Analysis
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General Information
AccessionDCA00039356
TitleInteraction network and enrichment analysis of genes upregulated in TMEM100 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between TMEM100 KO cells and control cells in the lung cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Mt1|Rgcc|Selenbp1|Sgk1|Lpl|Atp1b1|Errfi1|Nupr1|Ly6a|Sphk1|Pnpla2|Ctsh|Sh3d21|Eif4h|Zfp36|Txnip|Lox|Stt3b|Hist1h1c|Ly6c1|Klf9|Herpud1|Ddit4|Scnn1a|Xdh
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
CREEDS IDgene:3024
Cell Typelung
Gene Symbol (human)TMEM100
Gene Symbol (mouse)Tmem100
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1378008, GSM1378009, GSM1378010
Perturbed SamplesGSM1378011, GSM1378012, GSM1378013
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE57256
Gene Expression Omnibus
Expression data from adult lungs isolated from TMEM100-deficient mice
7
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