Interaction network and enrichment analysis of genes downregulated in SIN3A Silencing - siRNA
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00039371
TitleInteraction network and enrichment analysis of genes downregulated in SIN3A Silencing - siRNA
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between SIN3A Silencing - siRNA cells and control cells in the Calu-3 airway epithelial cells cell type.
Analysis URLhttp://genemania.org/#/search/human/CSN3|CANX|RCN1|SPP1|CDC6|SNORD13|HSPA8|HSP90AB1|HSP90B1|TAF15|SSB|TOP2A|CHPT1|HIST1H4C|RN7SL2|HSD17B4|C6orf62|ANXA4|HNRNPH1|HNRNPK|PSMA2|NUCKS1|CBX5|H2AFZ|TMBIM6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:3038
Cell TypeCalu-3 airway epithelial cells
Gene Symbol (human)SIN3A
Gene Symbol (mouse)Sin3a
Organismhuman
Perturbation TypeSilencing - siRNA
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM952740, GSM952741, GSM952742, GSM952746, GSM952747, GSM952748
Perturbed SamplesGSM952743, GSM952744, GSM952745
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38956
Gene Expression Omnibus
Cystic fibrosis transmembrane conductance regulator expression in airway epithelial cells
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.