Interaction network and enrichment analysis of genes upregulated in PTRF KO
Canned Analysis
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General Information
AccessionDCA00039470
TitleInteraction network and enrichment analysis of genes upregulated in PTRF KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between PTRF KO cells and control cells in the lung cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Inmt|Rgcc|Rpl10a|Rpl9|Rplp2|Gpx3|Rps16|Gm6988|Ppia|Rps9|Uba52|Rpl18|Rps14|Rpl26|Eif3f|Rps10|Txnip|Rpl35|Gm12816|Rps7|Ubg|Stfa1|Klf9|Rpl18a|ND4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3105
Cell Typelung
Gene Symbol (human)PTRF
Gene Symbol (mouse)Ptrf
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1065357, GSM1065358, GSM1065359, GSM1065360, GSM1065361, GSM1065362
Perturbed SamplesGSM1065351, GSM1065352, GSM1065353, GSM1065354, GSM1065355, GSM1065356
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43561
Gene Expression Omnibus
Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking Cavin-1/PTRF
7
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