Interaction network and enrichment analysis of genes downregulated in IFNL3 mutant (SNP polymorphism)
Canned Analysis
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General Information
AccessionDCA00039477
TitleInteraction network and enrichment analysis of genes downregulated in IFNL3 mutant (SNP polymorphism)
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between IFNL3 mutant (SNP polymorphism) cells and control cells in the Analysis of resected liver from hepatocellular carcinoma (HCC) patients with chronic hepatitis C (CHC) cell type.
Analysis URLhttp://genemania.org/#/search/human/CRP|FABP1|FGL1|PLA2G2A|HSPA1B|SAA2|G6PC|HSP90AA1|ALB|SERPINA7|LECT2|CYP3A5|NNMT|IGFBP1|SPINK1|PHYH|ITIH3|ORM1|H19|VTN|CYP2A6|CYP2E1|LOC100510047|SERPINF1|HSPA1A
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curator
CREEDS ID
Cell Type
Gene Symbol (human)
Gene Symbol (mouse)
Organism
Perturbation Type
Characteristic Direction parameters
Gene Set
Gene Set Size
Control Samples
Perturbed Samples
Tools used in the analysis

Keyword
Dataset Accession

GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis

Keyword
Tool Name

GSE41804
IL-28B polymorphism effect on hepatitis C virus-related hepatocellular carcinoma: resected liver
21
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