Interaction network and enrichment analysis of genes upregulated in TNF Stimulation of gene product
Canned Analysis
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General Information
AccessionDCA00039488
TitleInteraction network and enrichment analysis of genes upregulated in TNF Stimulation of gene product
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between TNF Stimulation of gene product cells and control cells in the Microvascular endothelial cells cell type.
Analysis URLhttp://genemania.org/#/search/human/CCL2|VCAM1|CXCL8|NFKBIA|MT2A|ICAM1|TNIP1|PTX3|MT1E|MT1H|FTH1|LOC100505584|DRAM1|BIRC2|SLC39A14|TNFAIP3|MT1X|GCH1|SERPINE1|SERPINE2|ISG15|GBP1|CXCL1|PALM2-AKAP2|SDC4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:3111
Cell TypeMicrovascular endothelial cells
Gene Symbol (human)TNF
Gene Symbol (mouse)Tnf
Organismhuman
Perturbation TypeStimulation of gene product
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM50771, GSM50772, GSM50773
Perturbed SamplesGSM50774, GSM50775, GSM50776
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2638
Gene Expression Omnibus
Tumor necrosis factor effect on microvascular endothelial cells
7
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