Interaction network and enrichment analysis of genes upregulated in PPARGC1A Deficiency
Canned Analysis
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General Information
AccessionDCA00039524
TitleInteraction network and enrichment analysis of genes upregulated in PPARGC1A Deficiency
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between PPARGC1A Deficiency cells and control cells in the Aged gastrocnemius muscle - 24 months cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Car3|Rps12|Myh7|Myl2|Rpl10|Rpl26|Hbb-bs|Rps27a|Ampd1|Rpl31-ps17|Cfd|Lgals1|Rpl18a|Rplp0|Gm12191|Rps5|Csrp3|Hspb1|Rps3a2|Rplp1|LOC100044627|Tnnc1|Bex1|Rpl31|Rpl4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:338
Cell TypeAged gastrocnemius muscle - 24 months
Gene Symbol (human)PPARGC1A
Gene Symbol (mouse)Ppargc1a
Organismmouse
Perturbation TypeDeficiency
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1269625, GSM1269626, GSM1269627
Perturbed SamplesGSM1269628, GSM1269629, GSM1269630
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52550
Gene Expression Omnibus
Peroxisome proliferator- coactivator-1 deficiency effect on aged gastrocnemius muscle
14
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