Interaction network and enrichment analysis of genes upregulated in HMX1 Deficiency
Canned Analysis
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General Information
AccessionDCA00039536
TitleInteraction network and enrichment analysis of genes upregulated in HMX1 Deficiency
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between HMX1 Deficiency cells and control cells in the Retinas of C57BL/6J cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Crygd|Xist|Cryaa|Cryba1|Crybb1|Crygs|Crygf|Mt2|Guca1a|Opn1sw|Cryga|Glo1|Hist3h2a|Pdzd8|Cd24a|Cmtm5|Aldoc|Crygc|Rpl15|Sacs|Ndrg2|Ip6k2|Folh1|Utp14b|Hist1h1c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:351
Cell TypeRetinas of C57BL/6J
Gene Symbol (human)HMX1
Gene Symbol (mouse)Hmx1
Organismmouse
Perturbation TypeDeficiency
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1142797, GSM1142798, GSM1142799, GSM1142800
Perturbed SamplesGSM1142793, GSM1142794, GSM1142795, GSM1142796
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47002
Gene Expression Omnibus
H6 family homoebox 1 deficiency effect on the retina
7
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