Interaction network and enrichment analysis of genes upregulated in SOX11 DEPLETION
Canned Analysis
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General Information
AccessionDCA00039540
TitleInteraction network and enrichment analysis of genes upregulated in SOX11 DEPLETION
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between SOX11 DEPLETION cells and control cells in the Z138 mantle cell lymphoma (MCL) cells cell type.
Analysis URLhttp://genemania.org/#/search/human/HSPA8|HSP90AA1|SETP4|HIST1H4C|PTGES3|RPL26|UBC|HSP90AB1|CCT2|FAM72A|IGJ|OSBPL9|CREG1|SLC38A2|HSPH1|FTH1P5|MRFAP1|TMED2|CAV1|IARS|PBK|CXCR4|PPP1CC|DNMT1|IARS2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:353
Cell TypeZ138 mantle cell lymphoma (MCL) cells
Gene Symbol (human)SOX11
Gene Symbol (mouse)Sox11
Organismhuman
Perturbation TypeDEPLETION
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM854802, GSM854803
Perturbed SamplesGSM854804, GSM854805
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34763
Gene Expression Omnibus
Neural transcription factor SOX11 depletion effect on mantle cell lymphoma cell line
7
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