Interaction network and enrichment analysis of genes downregulated in KLF15 KO
Canned Analysis
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General Information
AccessionDCA00039641
TitleInteraction network and enrichment analysis of genes downregulated in KLF15 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between KLF15 KO cells and control cells in the heart cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Pln|Bsg|Hadha|LOC100048117|Cox6a2|Got1|Ech1|Txnip|Hbb-bs|Acaa2|Myh6|Lpl|Dcn|Got2|Actn2|Tecr|Fxyd1|Atp5g1|Ttn|Fabp3|Hspb7|Fhl2|Sqstm1|Oaz1-ps|6720475J19Rik
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorzero323
CREEDS IDgene:446
Cell Typeheart
Gene Symbol (human)KLF15
Gene Symbol (mouse)Klf15
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1288174, GSM1288175, GSM1288176, GSM1288177
Perturbed SamplesGSM1288178, GSM1288179, GSM1288180
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE53231
Gene Expression Omnibus
KLF14-deficient hearts during fasting
7
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