Interaction network and enrichment analysis of genes downregulated in GFI1B OE
Canned Analysis
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General Information
AccessionDCA00039649
TitleInteraction network and enrichment analysis of genes downregulated in GFI1B OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between GFI1B OE cells and control cells in the AMuLV (pro-B Abelson leukemia virus transformed) cell line cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Cd53|Vim|Gimap4|Fetub|Ctss|Tfrc|Klhdc2|B230118H07Rik|Ezh2|Tpm4|Ighv1-72|Lgals1|Blk|Milr1|Rgs18|Atp1b3|Sae1|Cpm|Tnks2|Arap2|Rdh10|Crhbp|Evl|Laptm5|Snx2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:452
Cell TypeAMuLV (pro-B Abelson leukemia virus transformed) cell line
Gene Symbol (human)GFI1B
Gene Symbol (mouse)Gfi1b
Organismmouse
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM833177, GSM833179, GSM833181
Perturbed SamplesGSM833178, GSM833180, GSM833182
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE33709
Gene Expression Omnibus
Gfi1b overexpression in a pro-B Abelson leukemia virus transformed cell line
7
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