Interaction network and enrichment analysis of genes downregulated in HMGA2 KO
Canned Analysis
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General Information
AccessionDCA00039677
TitleInteraction network and enrichment analysis of genes downregulated in HMGA2 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between HMGA2 KO cells and control cells in the lung (E18.5) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Lyz1|Chil1|Scd1|Cxcl15|Cbr2|Scgb1a1|Lyz2|Sftpa1|Slc34a2|Trf|Fn1|Sftpb|Lcn2|Emp2|Hc|Ager|Timp3|Vnn1|Lamp3|Ctsh|Tmem243|Ifitm3|Igfbp7|Gprc5a|Scn7a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcarlfulp
CREEDS IDgene:48
Cell Typelung (E18.5)
Gene Symbol (human)HMGA2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM1334375, GSM1334376
Perturbed SamplesGSM1334377, GSM1334378
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE55340
Gene Expression Omnibus
High Mobility Group AT-hook Protein 2 deficiency effect on the embryonic lung
7
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