Interaction network and enrichment analysis of genes upregulated in SIRT4 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00039686
TitleInteraction network and enrichment analysis of genes upregulated in SIRT4 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between SIRT4 KO cells and control cells in the Liver cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Cyp2c39|Rgn|Hbb-bs|Sult1a1|Hba-a2|Hspa1b|Pon1|Elovl5|Cyp1a2|Pigr|Cyp7a1|Acaa1b|Cyp2c50|Cyp2c54|Aldh1a1|G0s2|Insig1|Bhmt|Tat|Ppap2b|Acot3|Ppp1r3b|Cdo1|Cyp8b1|Ces1d
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlhs
CREEDS IDgene:49
Cell TypeLiver
Gene Symbol (human)SIRT4
Gene Symbol (mouse)Sirt4
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1359081, GSM1359082, GSM1359083, GSM1359084, GSM1359085, GSM1359086
Perturbed SamplesGSM1359087, GSM1359088, GSM1359089, GSM1359090, GSM1359091, GSM1359092
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE56321
Gene Expression Omnibus
SIRT4 deficiency effect on the liver
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.