Interaction network and enrichment analysis of genes upregulated in HIF1AN Deficiency
Canned Analysis
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General Information
AccessionDCA00039732
TitleInteraction network and enrichment analysis of genes upregulated in HIF1AN Deficiency
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between HIF1AN Deficiency cells and control cells in the Immortalized embryonic fibroblasts cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Rps12|Rps3a2|Rps27a|LOC630855|Rpl39-ps|Psmb7|Rpl31-ps17|Ino80|Gm5805|Nme2|Chchd2|Rpl11|Oaz1|Rps23|LOC100044627|Vim|Gm10335|Gm12191|Rplp0|Rpl7a|Rpl32|Rps7|Gm10269|S100a4|Rplp2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:538
Cell TypeImmortalized embryonic fibroblasts
Gene Symbol (human)HIF1AN
Gene Symbol (mouse)Hif1an
Organismmouse
Perturbation TypeDeficiency
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM509574, GSM509575
Perturbed SamplesGSM509576, GSM509577
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE20335
Gene Expression Omnibus
Asparaginyl Hydroxylase Factor inhibiting HIF-1 (FIH) deficiency effect on immortalized embryonic fibroblasts
14
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