Interaction network and enrichment analysis of genes upregulated in EZH2 KO
Canned Analysis
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General Information
AccessionDCA00039740
TitleInteraction network and enrichment analysis of genes upregulated in EZH2 KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between EZH2 KO cells and control cells in the Primary preadipocyte cultures cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Crabp1|Mgp|Cst3|Lgals3|Ly6a|Spcs3|Mt2|Hspb1|Spp1|S100a4|Pcolce|Cd24a|Crlf1|H2afx|Hmgn2-ps1|Uqcrh|Ccl2|Prl2c4|Lsm4|Snrpe|Ly6c2|Prickle4|Lxn|Ube2c|Hist1h2ao
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:542
Cell TypePrimary preadipocyte cultures
Gene Symbol (human)EZH2
Gene Symbol (mouse)Ezh2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM501365, GSM501366
Perturbed SamplesGSM501363, GSM501364
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20054
Gene Expression Omnibus
Histone H3K27 methyltransferase Ezh2 deletion effect on primary preadipocyte cultures
7
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