Interaction network and enrichment analysis of genes upregulated in PAX5 OE
Canned Analysis
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General Information
AccessionDCA00039778
TitleInteraction network and enrichment analysis of genes upregulated in PAX5 OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between PAX5 OE cells and control cells in the L428-PAX5 cell type.
Analysis URLhttp://genemania.org/#/search/human/HIST1H4H|USP17L9P|SNORA45A|RN7SL2|ZNF595|SNORA71D|NBPF20|ARL6IP1|ENPP2|SNORD41|GUSBP1|RNU1-1|HIST1H3H|USP17L20|SNHG3|GUSBP9|LGMN|USP17L6P|RMRP|SMG1P5|TUBB4B|SMG1P3|NPIPB5|PEG10|HIST1H2AG
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:575
Cell TypeL428-PAX5
Gene Symbol (human)PAX5
Gene Symbol (mouse)Pax5
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1081178, GSM1081179, GSM1081180
Perturbed SamplesGSM1081190, GSM1081191, GSM1081192
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44244
Gene Expression Omnibus
Transcription factor Pax5 overexpression in Hodgkin lymphoma cell line L428
14
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