Interaction network and enrichment analysis of genes downregulated in MIR140 Silencing
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00039807
TitleInteraction network and enrichment analysis of genes downregulated in MIR140 Silencing
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MIR140 Silencing cells and control cells in the C3H10T1/2 fibroblast cell line cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Col1a1|Rps15|Rps14|Col2a1|Actb|Gm10335|Rpl28|Rplp1|Erdr1|Col6a3|BC094435|Fn1|Eno1b|Bmp4|Rps2-ps6|Rps8|Atf5|Cdsn|Col6a2|Rps27rt|Prpf8|Rpl23|Ftl1|Rpl36a|Gm10094
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:601
Cell TypeC3H10T1/2 fibroblast cell line
Gene Symbol (human)MIR140
Organismmouse
Perturbation TypeSilencing
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM341742, GSM341743, GSM341744
Perturbed SamplesGSM341737, GSM341739, GSM341740
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE13590
Gene Expression Omnibus
microRNA-140 silencing effect on fibroblast cell line
14
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.