Interaction network and enrichment analysis of genes downregulated in PCDH12 Deficiency
Canned Analysis
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General Information
AccessionDCA00039811
TitleInteraction network and enrichment analysis of genes downregulated in PCDH12 Deficiency
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between PCDH12 Deficiency cells and control cells in the Embryonic placentas (12.5 day) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Prl6a1|Car2|Prl7b1|Ceacam11|1600012P17Rik|Hist1h2ao|Ceacam14|Gm5805|LOC630855|Gzmd|Rpl34|Rps2|Rps7|Gzme|Rps2-ps6|Rps5|Rpl11|LOC100048552|Rpl32|Rpl19|Ino80|Gzmg|Rps27a|Rps12|Rpl7a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:604
Cell TypeEmbryonic placentas (12.5 day)
Gene Symbol (human)PCDH12
Gene Symbol (mouse)Pcdh12
Organismmouse
Perturbation TypeDeficiency
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM185959, GSM185960, GSM185961, GSM185962, GSM185963
Perturbed SamplesGSM185954, GSM185955, GSM185956, GSM185957, GSM185958
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE7676
Gene Expression Omnibus
Protocadherin 12 deficiency effect on the placenta
7
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