Interaction network and enrichment analysis of genes downregulated in PAX3 Knock-in
Canned Analysis
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General Information
AccessionDCA00039853
TitleInteraction network and enrichment analysis of genes downregulated in PAX3 Knock-in
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between PAX3 Knock-in cells and control cells in the Palatal shelves (E14.5 embryos - palate) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Lum|Erdr1|Spp1|Rpl26|Ogn|Gpc3|Col1a2|Col1a1|Col5a2|B230214O09Rik|Tuba1b|Col3a1|Actc1|Cthrc1|Serpine2|Sfrp2|Serpinh1|Ifitm5|Bud31|Col11a1|Col6a3|Cap1|Gt(ROSA)26Sor|Xist|Col2a1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:625
Cell TypePalatal shelves (E14.5 embryos - palate)
Gene Symbol (human)PAX3
Gene Symbol (mouse)Pax3
Organismmouse
Perturbation TypeKnock-in
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM287783, GSM287784, GSM287787, GSM287788
Perturbed SamplesGSM287781, GSM287782, GSM287785, GSM287786
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11400
Gene Expression Omnibus
Transcription factor paired box 3 knockin embryos: palate
7
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