Interaction network and enrichment analysis of genes upregulated in GLI1 INHIBITION
Canned Analysis
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General Information
AccessionDCA00039878
TitleInteraction network and enrichment analysis of genes upregulated in GLI1 INHIBITION
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between GLI1 INHIBITION cells and control cells in the Panc-1 cells cell type.
Analysis URLhttp://genemania.org/#/search/human/ARRB1|HIST1H3I|HIST1H2BM|KRT19|SDC4|ITGA5|CX3CL1|CCL5|IFNL3|ICAM1|ETS2|TSPAN15|FAM102A|RHPN2|F8A3|HLA-B|MAT2A|SEMA4B|SLCO4A1|HIST1H1E|SERPINE1|B4GALT5|TUBB4B|RAB31|SMAD3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvmathur
CREEDS IDgene:643
Cell TypePanc-1 cells
Gene Symbol (human)GLI1
Gene Symbol (mouse)Gli1
Organismhuman
Perturbation TypeINHIBITION
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM904693, GSM904694, GSM904695
Perturbed SamplesGSM904696, GSM904697, GSM904698
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36855
Gene Expression Omnibus
Gli transcriptional repressor Gli3T effect on epithelioid carcinoma cell line Panc-1
7
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