Interaction network and enrichment analysis of genes upregulated in NOTCH1 Deficiency
Canned Analysis
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General Information
AccessionDCA00039904
TitleInteraction network and enrichment analysis of genes upregulated in NOTCH1 Deficiency
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between NOTCH1 Deficiency cells and control cells in the Hair follicles cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Krtap8-1|Krt31|Mt4|Krt33a|Krtap11-1|Rpl39-ps|Zfp526|Hspb1|Tuba1b|S100a3|Gm5805|Krt71|Rps15|Rpl18a|Dct|Fabp5|Sprr1a|Rpl19|Dstn|Rpl7|Gm10335|Rps3a2|Krt32|Rplp2|Eef1a1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:662
Cell TypeHair follicles
Gene Symbol (human)NOTCH1
Gene Symbol (mouse)Notch1
Organismmouse
Perturbation TypeDeficiency
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM158362, GSM158363
Perturbed SamplesGSM158359, GSM158361
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6867
Gene Expression Omnibus
Notch1 deficiency effect on hair follicles
7
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