Interaction network and enrichment analysis of genes downregulated in SMARCA4 DEPLETION
Canned Analysis
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General Information
AccessionDCA00039984
TitleInteraction network and enrichment analysis of genes downregulated in SMARCA4 DEPLETION
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between SMARCA4 DEPLETION cells and control cells in the Embryos (maternally depleted) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Gm11544|Gm6176|Gm3601|Gm12789|Gm7056|Nme2|Hirip3|Dek|Oser1|Lmo1|Thap11|Prps1|Timd2|2410004B18Rik|Utp14b|AA545190|G6pdx|Ubtfl1|Pabpc4|Fhod3|Prpsap1|Rpl31-ps17|LOC100041885|Slc34a2|Mki67
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:747
Cell TypeEmbryos (maternally depleted)
Gene Symbol (human)SMARCA4
Gene Symbol (mouse)Smarca4
Organismmouse
Perturbation TypeDEPLETION
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM122519, GSM122520, GSM122521, GSM122522
Perturbed SamplesGSM122523, GSM122524, GSM122525, GSM122526
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5371
Gene Expression Omnibus
BRG1 maternally depleted embryos
7
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