Interaction network and enrichment analysis of genes upregulated in LHX1 NULL MUTATION - Ablation
Canned Analysis
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General Information
AccessionDCA00040005
TitleInteraction network and enrichment analysis of genes upregulated in LHX1 NULL MUTATION - Ablation
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between LHX1 NULL MUTATION - Ablation cells and control cells in the Embryonic kidneys (from day E18.5) cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Sprr2f|Erdr1|Hba-a2|Nedd4|Gsdmc|Gsdmc2|Rpl28|Hsp90ab1|Mdk|Mest|S100a11|Sfrp2|Crisp1|D17H6S56E-5|Tubb5|Flna|Penk|Id4|Nrep|Trim28|Cfh|Sepp1|Set|H19|Marcksl1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:776
Cell TypeEmbryonic kidneys (from day E18.5)
Gene Symbol (human)LHX1
Gene Symbol (mouse)Lhx1
Organismmouse
Perturbation TypeNULL MUTATION - Ablation
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM96567, GSM96568
Perturbed SamplesGSM96569, GSM96570
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4230
Gene Expression Omnibus
Homeobox Lim1 mutant nephron-deficient kidneys
14
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