Interaction network and enrichment analysis of genes downregulated in CTNNB1 Activation (deltaNB-cateninER transgenics)
Canned Analysis
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General Information
AccessionDCA00040014
TitleInteraction network and enrichment analysis of genes downregulated in CTNNB1 Activation (deltaNB-cateninER transgenics)
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between CTNNB1 Activation (deltaNB-cateninER transgenics) cells and control cells in the Skin - 0 Day cell type.
Analysis URLhttp://genemania.org/#/search/mouse/Myh4|Rpl36a|Hp|Retn|Rnase4|Fasn|Thrsp|Rpl14|Hbb-bs|Stard7|Gpx1|Tkt|Iscu|H2-K1|Pkp1|Chchd2|Golga7|Ctsd|Igfbp6|Crip1|Tmem45a|S100a10|Shisa5|Msmo1|Ccl6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:793
Cell TypeSkin - 0 Day
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation TypeActivation (deltaNB-cateninER transgenics)
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size50
Control SamplesGSM26945, GSM26946, GSM26947
Perturbed SamplesGSM26935, GSM26938
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1579
Gene Expression Omnibus
Beta-catenin activation effect on skin: time course
21
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