Interaction network and enrichment analysis of genes upregulated in RRP1B OE
Canned Analysis
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General Information
AccessionDCA00040043
TitleInteraction network and enrichment analysis of genes upregulated in RRP1B OE
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between RRP1B OE cells and control cells in the cell line MDA-MB-231 cell type.
Analysis URLhttp://genemania.org/#/search/human/UCA1|GSTP1|PPME1|LY6E|TRIM16L|SLC25A6|AKR1B1|LRRC61|THBS1|BMP4|MED14|CTSD|STRADB|NQO1|CDA|RRP1B|TACSTD2|SDC4|CST7|FTL|GPX4|KRT7|CYBRD1|RHOBTB3|PLAC8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormtahay
CREEDS IDgene:821
Cell Typecell line MDA-MB-231
Gene Symbol (human)RRP1B
Gene Symbol (mouse)Rrp1b
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM1304753, GSM1304754, GSM1304755, GSM1304756, GSM1304757
Perturbed SamplesGSM1304748, GSM1304749, GSM1304750, GSM1304751, GSM1304752
Tools used in the analysis
Keyword
Dataset Accession
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53979
Gene Expression Omnibus
Expression data from MDA-MB-231 cells over-expressing RRP1B and MDA-MB-231 control cells with endogenous RRP1B levels
7
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