Interaction network and enrichment analysis of genes upregulated in LMX1B KO
Canned Analysis
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General Information
AccessionDCA00040057
TitleInteraction network and enrichment analysis of genes upregulated in LMX1B KO
DescriptionThe analysis explores the gene interaction network and pathway enrichment of the top 50 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between LMX1B KO cells and control cells in the embryonic (e11.5) proximal hindlimb bud tissues cell type.
Analysis URLhttp://genemania.org/#/search/mouse/BC094435|Hbb-bs|Hbb-y|Hmgn2-ps1|Gm10128|Gpc3|Col3a1|Hba-a2|H19|Gga2|Sertad4|Xist|Atp5g3|Cdkn1c|Lgals1|Tma7|Cap1|Hbb-bh1|Igfbp5|Hba-x|Bex1|Rplp1|Igf2|LOC100503721|Eif2s3x
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:84
Cell Typeembryonic (e11.5) proximal hindlimb bud tissues
Gene Symbol (human)LMX1B
Gene Symbol (mouse)Lmx1b
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size50
Control SamplesGSM264689, GSM264690, GSM264691
Perturbed SamplesGSM264692, GSM264693, GSM264694
Tools used in the analysis
Keyword
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
Datasets used in the analysis
Keyword
Tool Name
GSE10516
Gene Expression Omnibus
Lmx1b knockout effect on embryonic proximal hindlimb buds
7
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