Muscle glycogen content effect on skeletal muscle
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE2198
TitleMuscle glycogen content effect on skeletal muscle
DescriptionAnalysis of skeletal muscles of MGSKO and GSL30 lines which lack or over-accumulate muscle glycogen, respectively. Liver was also analyzed in MGSKO to assess whether muscle glycogen loss has indirect effects on liver. The two largest glycogen stores in mammals are in skeletal muscle and liver.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2198
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Pert Type
Geneset

Small molecules which mimic GYS1 KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse GYS1 KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic GYS1 KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse GYS1 KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic GYS1 KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse GYS1 KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic GYS1 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse GYS1 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in GYS1 KO
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated in GYS1 KO
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
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