Type 2 diabetes and role of hepatokines
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE23343
TitleType 2 diabetes and role of hepatokines
DescriptionAnalysis of percutaneous needle liver biopsies from 10 people with type 2 diabetes (T2D) and 7 normal subjects. The liver has a central role in glucose homeostasis and is a major site of secretory protein production. Results provide insight into the role of hepatokines in T2D insulin resistance.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE23343
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Geneset

Interaction network and enrichment analysis of genes downregulated in type 2 diabetes mellitus
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in type 2 diabetes mellitus
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes downregulated in type 2 diabetes mellitus
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in type 2 diabetes mellitus
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Small molecules which mimic type 2 diabetes mellitus
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse type 2 diabetes mellitus
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic type 2 diabetes mellitus
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse type 2 diabetes mellitus
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in type 2 diabetes mellitus
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated in type 2 diabetes mellitus
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
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