Embryonic stem cell line response to the conditional expression of neurogenin 3
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE3653
TitleEmbryonic stem cell line response to the conditional expression of neurogenin 3
DescriptionAnalysis of transgenic embryonic stem cells induced with doxycycline to express neurogenin 3 (Ngn3) and differentiated for 3 or 10 days as embryoid bodies. Ngn3 is required for pancreatic islet development. Results provide insight into Ngn3-regulated molecular events during development.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3653
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Pert Type
Geneset

Small molecules which mimic NEUROG3 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse NEUROG3 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic NEUROG3 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse NEUROG3 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic NEUROG3 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse NEUROG3 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic NEUROG3 Conditional expression (induced with doxycycline)
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse NEUROG3 Conditional expression (induced with doxycycline)
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic NEUROG3 Conditional expression (induced with doxycycline)
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse NEUROG3 Conditional expression (induced with doxycycline)
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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