Melanoma progression
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE4587
TitleMelanoma progression
DescriptionAnalysis of tissue specimens representing benign nevus, atypical nevus, melanoma in situ, vertical growth phase (VGP) melanoma, and metastatic growth phase (MGP) melanoma. Results identify expression signatures that distinguish benign and atypical nevi and melanomas in situ from VGPs and MGPs.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE4587
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Disease Name
Geneset

Interaction network and enrichment analysis of genes downregulated in melanoma
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in melanoma
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes downregulated in melanoma in situ
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Interaction network and enrichment analysis of genes upregulated in melanoma in situ
The analysis explores the gene interaction network and pathway enrichment of the top 50 mo...
Small molecules which mimic melanoma
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse melanoma
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic melanoma in situ
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse melanoma in situ
The L1000 database was queried in order to identify small molecule perturbations which rev...
Enrichment analysis of genes dysregulated in melanoma
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
Enrichment analysis of genes dysregulated in melanoma in situ
An enrichment analysis was performed on the top most dyresgulated genes determined by appl...
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