Diabetes and Obesity Regulated gene gain-of-function effect on skeletal muscle
Transcriptomics Dataset
FAIR Metrics
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General Information
AccessionGSE54917
TitleDiabetes and Obesity Regulated gene gain-of-function effect on skeletal muscle
DescriptionAnalysis of quadriceps from a muscle-specific, Diabetes and Obesity Regulated gene (DOR; also named Tp53inp2) overexpression line (SKM-Tg). DOR gain of function causes a reduction in muscle mass. Results provide insight into the functional role of DOR in skeletal muscle.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE54917
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Keyword
Dataset Accession

Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
GeneMANIA
Published June 2010
Biological network integration for gene prioritization and predicting gene function
7435
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Canned Analyses generated with the dataset

Dataset Accession
Tool Name
Direction
Cell Type
Disease Name
Pert Type
Geneset

Small molecules which mimic TP53INP2 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse TP53INP2 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic TP53INP2 KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse TP53INP2 KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic TP53INP2 KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse TP53INP2 KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic TP53INP2 KO
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse TP53INP2 KO
The L1000 database was queried in order to identify small molecule perturbations which rev...
Small molecules which mimic TP53INP2 OE
The L1000 database was queried in order to identify small molecule perturbations which mim...
Small molecules which reverse TP53INP2 OE
The L1000 database was queried in order to identify small molecule perturbations which rev...
...
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