BreakFusion
Computational Tool
FAIR Metrics
0 evaluations
General Information
DescriptionTargeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data
Homepagehttp://bioinformatics.mdanderson.org/main/BreakFusion
Publications
BreakFusion: targeted assembly-based identification of gene fusions in whole transcriptome paired-end sequencing data
Ken Chen; John W. Wallis; Cyriac Kandoth; Joelle M. Kalicki−Veizer; Karen L. Mungall; Andrew J. Mungall; Steven J. Jones; Marco A. Marra; Timothy J. Ley; Elaine R. Mardis; Richard K. Wilson; John N. Weinstein; Li Ding
Summary: Despite recent progress, computational tools that identify gene fusions from next-generation whole transcriptome sequencing data are often limited in accuracy and scalability. Here, we present a software package, BreakFusion that combines the strength of reference alignment followed by read-pair analysis and de novo assembly to achieve a good balance in sensitivity, specificity and computational efficiency.
Availability: http://bioinformatics.mdanderson.org/main/BreakFusion
Contact: kchen3@mdanderson.org; lding@genome.wustl.edu
Supplementary information: Supplementary data are available at Bioinformatics online
DOI: https://doi.org/10.1093/bioinformatics/bts272
Metrics:
29
Canned Analyses generated by the tool
There are no indexed analyses by this tool at the moment.
Datasets analyzed by the tool
There are no indexed analyses by this tool at the moment.
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.