ICT
Computational Tool
FAIR Metrics
0 evaluations
General Information
DescriptionIsotope correction toolbox
Homepagehttps://github.com/jungreuc/isotope_correction_toolbox/
Publications
ICT: isotope correction toolbox
Christian Jungreuthmayer; Stefan Neubauer; Teresa Mairinger; Jürgen Zanghellini; Stephan Hann
Summary: Isotope tracer experiments are an invaluable technique to analyze and study the metabolism of biological systems. However, isotope labeling experiments are often affected by naturally abundant isotopes especially in cases where mass spectrometric methods make use of derivatization. The correction of these additive interferences—in particular for complex isotopic systems—is numerically challenging and still an emerging field of research. When positional information is generated via collision-induced dissociation, even more complex calculations for isotopic interference correction are necessary. So far, no freely available tools can handle tandem mass spectrometry data. We present isotope correction toolbox, a program that corrects tandem mass isotopomer data from tandem mass spectrometry experiments. Isotope correction toolbox is written in the multi-platform programming language Perl and, therefore, can be used on all commonly available computer platforms.
Availability and implementation: Source code and documentation can be freely obtained under the Artistic License or the GNU General Public License from: https://github.com/jungreuc/isotope_correction_toolbox/
Contact: {christian.jungreuthmayer@boku.ac.at,juergen.zanghellini@boku.ac.at}
Supplementary information: Supplementary data are available at Bioinformatics online.
DOI: https://doi.org/10.1093/bioinformatics/btv514
Metrics:
4
Canned Analyses generated by the tool
There are no indexed analyses by this tool at the moment.
Datasets analyzed by the tool
There are no indexed analyses by this tool at the moment.
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.