NGS++
Computational Tool
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General Information
DescriptionA library for rapid prototyping of epigenomics software tools
Homepagehttps://github.com/NGS-lib/NGSplusplus
Publications
NGS++: a library for rapid prototyping of epigenomics software tools
Alexei Nordell Markovits; Charles Joly Beauparlant; Dominique Toupin; Shengrui Wang; Arnaud Droit; Nicolas Gevry
Motivation: The development of computational tools to enable testing and analysis of high-throughput–sequencing data is essential to modern genomics research. However, although multiple frameworks have been developed to facilitate access to these tools, comparatively little effort has been made at implementing low-level programming libraries to increase the speed and ease of their development.
Results: We propose NGS++, a programming library in C++11 specialized in manipulating both next-generation sequencing (NGS) datasets and genomic information files. This library allows easy integration of new formats and rapid prototyping of new functionalities with a focus on the analysis of genomic regions and features. It offers a powerful, yet versatile and easily extensible interface to read, write and manipulate multiple genomic file formats. By standardizing the internal data structures and presenting a common interface to the data parser, NGS++ offers an effective framework for epigenomics tool development.
Availability: NGS++ was written in C++ using the C++11 standard. It requires minimal efforts to build and is well-documented via a complete docXygen guide, online documentation and tutorials. Source code, tests, code examples and documentation are available via the website at http://www.ngsplusplus.ca and the github repository at https://github.com/NGS-lib/NGSplusplus.
Contact: nicolas.gevry@usherbrooke.ca or arnaud.droit@crchuq.ulaval.ca
DOI: https://doi.org/10.1093/bioinformatics/btt312
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