PIE the search | Datasets2Tools

General Information

Description	Searching PubMed literature for protein interaction information
Homepage	http://www.ncbi.nlm.nih.gov/IRET/PIE/

Publications

Bioinformatics (2011)

PIE the search: searching PubMed literature for protein interaction information

Sun Kim; Dongseop Kwon; Soo-Yong Shin; W. John Wilbur

Motivation: Finding protein-protein interaction (PPI) information from literature is challenging but an important issue. However, keyword search in PubMed® is often time consuming because it requires a series of actions that refine keywords and browse search results until it reaches a goal. Due to the rapid growth of biomedical literature, it has become more difficult for biologists and curators to locate PPI information quickly. Therefore, a tool for prioritizing PPI informative articles can be a useful assistant for finding this PPI-relevant information.

Results: PIE (Protein Interaction information Extraction) the search is a web service implementing a competition-winning approach utilizing word and syntactic analyses by machine learning techniques. For easy user access, PIE the search provides a PubMed-like search environment, but the output is the list of articles prioritized by PPI confidence scores. By obtaining PPI-related articles at high rank, researchers can more easily find the up-to-date PPI information, which cannot be found in manually curated PPI databases.

Availability: http://www.ncbi.nlm.nih.gov/IRET/PIE/

Contact: sun.kim@nih.gov

Supplementary information: Supplementary data are available at Bioinformatics online.

DOI: https://doi.org/10.1093/bioinformatics/btr702

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