General Information
| Description | A tool for the creation and use of positional priors in motif discovery |
| Homepage | http://tare.medisin.ntnu.no/priorseditor |
Publications
PriorsEditor: a tool for the creation and use of positional priors in motif discovery
Summary:
Computational methods designed to discover transcription factor binding sites in DNA sequences often have a tendency to make a lot of false predictions. One way to improve accuracy in motif discovery is to rely on positional priors to focus the search to parts of a sequence that are considered more likely to contain functional binding sites. We present here a program called PriorsEditor that can be used to create such positional priors tracks based on a combination of several features, including phylogenetic conservation, nucleosome occupancy, histone modifications, physical properties of the DNA helix and many more.
Availability:
PriorsEditor is available as a web start application and downloadable archive from http://tare.medisin.ntnu.no/priorseditor (requires Java 1.6). The web site also provides tutorials, screenshots and example protocol scripts.
Contact:
kjetil.klepper@ntnu.no
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