nCal
Computational Tool
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General Information
DescriptionAn R package for non-linear calibration
Homepagehttp://research.fhcrc.org/youyifong/en/resources/ncal.html
Publications
nCal: an R package for non-linear calibration
Youyi Fong; Krisztian Sebestyen; Xuesong Yu; Peter Gilbert; Steve Self
Summary: Non-linear calibration is a widely used method for quantifying biomarkers wherein concentration-response curves estimated using samples of known concentrations are used to predict the biomarker concentrations in the samples of interest. The R package nCal fills an important gap in the open source, stand-alone software for performing non-linear calibration. For curve fitting, nCal provides a new implementation of a robust, Bayesian hierarchical five-parameter logistic model. nCal supports a simple graphical user interface that can be used by laboratory scientists, and contains functionality for importing data from the multiplex bead array assay instrumentation.
Availability: The R package ‘nCal’ is available from http://cran.r-project.org/web/packages/nCal/ under GPL-2 or later.
Contact: yfong@fhcrc.org
Supplementary information: Supplementary information is available in the form of an R package vignette at the above repository and an FAQ at http://research.fhcrc.org/youyifong/en/resources/ncal.html.
Metrics:
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