This is a permanent results page for your analyzed data. Please save the link in your browser's address bar.
| Title / Description | Analysis of global changes in gene expression induced by human polynucleotide phosphorylase (hPNPaseold-35) |
| Accession | GSE53604 |
| Summary | Human Polynucleotide Phosphorylase (hPNPaseold-35) is an evolutionarily conserved 3’→5’ exoribonuclease implicated in the regulation of numerous physiological processes like maintenance of mitochondrial homeostasis, mtRNA import and aging-associated inflammation. From an RNase perspective, little is known about the RNA or miRNA species it targets for degradation or whose expression it regulates; except for c-myc and miR-221. |
| Organism | Homo sapiens |
| Platform | GPL571 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Gene | PNPT1 |
| Cell | HO1 |
| Perturbation | Knockdown |
| Relevant disease | Melanoma |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
| Up |
|
|||
| Down |
|
|||
| Combined |
|
|
|
