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| Title / Description | Estrogen Coordinates Translation and Transcription Revealing a Role for NRSF in Human Breast Cancer Cells |
| Accession | GSE18592 |
| Summary | Analysis of estrogen receptor (ER)-positive MCF7 cell total RNA expression and polysome-assiciated RNA expression following treatment with estradiol (E2) and vehicle (etoh). We used expression microarrays to measure polysome association and total RNA abundance in E2 treated MCF7. These data, along with previously published data, show that genes that are upregulated by estrogen treatment are biased towards association with polysomes. |
| Organism | Homo sapiens |
| Platform | GPL6244 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Organism | Homo sapiens |
| Cell_type | MCF7cells |
| Pert_name | estrogen |
| Pert_id | CHEBI:50114 |
| Organism | human |
| Pert_type | chemical |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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