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| Title / Description | Expression data from embryonic stem cells differentiation |
| Accession | GSE58960 |
| Summary | Pluripotency-associated transcription factor Foxd3 is required for maintaining pluripotent cells. However, the molecular mechanisms underlying its function are largely unknown. Here, we report that Foxd3 maintains the ESC identity through counteracting differentiation induction of Calcienurin-NFAT signaling. We used microarrays to detail the global programme of gene expression underlying overexpression of Foxd3 and NFATc3 in ESCs or deletion of Foxd3 in ESCs |
| Organism | Mus musculus |
| Platform | GPL1261 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Gene | FOXD3 |
| Cell | Embryonic Stem Cells |
| Perturbation | FOXD3 Conditional Knockout & Tamoxifen |
| Disease | Pluripotency and Differentiation |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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