LQTS gene signatures (101)

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Title Organism Platform Optional Metadata
1 Tamoxifen-resistant breast cancer cell line ... Homo sapiens Homo sapiens
Cell MCF7 Breast Tumor ...
Perturbation Tamoxifen
Disease Breast Cancer
2 Tamoxifen-resistant breast cancer cell line ... Homo sapiens Homo sapiens
Cell MCF7 Breast Tumor ...
Perturbation Tamoxifen
Disease Breast Cancer
3 Tamoxifen-resistant breast cancer cell line ... Homo sapiens Homo sapiens
Cell MCF7 Breast Tumor ...
Perturbation Tamoxifen
Disease Breast Cancer
4 Estrogen receptor alpha/beta heterodimer ... Homo sapiens Homo sapiens
Cell U2OS Osteosarcoma
Perturbation Tamoxifen (Estrogen ...
Disease Osteosarcoma
5 Estrogen receptor alpha/beta heterodimer ... Homo sapiens Homo sapiens
Cell U2OS Osteosarcoma
Perturbation Tamoxifen (Estrogen ...
Disease Osteosarcoma
6 Estrogen receptor alpha/beta heterodimer ... Homo sapiens Homo sapiens
Cell U2OS Osteosarcoma
Perturbation Tamoxifen (Estrogen ...
Disease Osteosarcoma
7 Transgenic model of selective ATF6 activation: ... Mus musculus Mus musculus
Cell Cardiac (Mus ...
Perturbation Tamoxifen
Disease Impaired Endoplasmic ...
8 Transgenic model of selective ATF6 activation: ... Mus musculus Mus musculus
Cell Cardiac (Mus ...
Perturbation Tamoxifen
Disease Impaired Endoplasmic ...
9 Tamoxifen-resistant breast cancer cell line ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer ...
Perturbation Tamoxifen
Disease Breast Cancer
10 Tamoxifen-resistant breast cancer cell line ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer ...
Perturbation Tamoxifen
Disease Breast Cancer
11 Proteasome inhibitor Bortezomib effect on MCF7 ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer
Perturbation Bortezomib
Disease Breast Cancer
12 Mepenzolate bromide effect on lung: time course Mus musculus Mus musculus
Cell Lung
Perturbation Mepenzolate (Time ...
Disease Chronic Obstructive ...
13 Mepenzolate bromide effect on lung: time course Mus musculus Mus musculus
Cell Lung
Perturbation Mepenzolate (Time ...
Disease Chronic Obstructive ...
14 Oncogenic BRAF harboring melanoma cell line ... Homo sapiens Homo sapiens
Cell A375 Melanoma cell
Perturbation Vemurafenib
Disease Melanoma
15 Antipsychotic agents clozapine and haloperidol ... Mus musculus Mus musculus
Cell Brain
Perturbation Clozapine
Disease Schizophrenia
16 Antipsychotic agents clozapine and haloperidol ... Mus musculus Mus musculus
Cell Brain
Perturbation Haloperidol
Disease Schizophrenia
17 Cirrhotic liver response to the ... Rattus norvegicus Rattus norvegicus
Cell Liver
Perturbation Sunitinib
Disease Cirrhosis
18 Adrenergic stress effect on transcription ... Mus musculus Mus musculus
Cell Cardiac (Wildtype)
Perturbation Phenylephrine
Disease Cardiac Hypertrophy
19 Adrenergic stress effect on transcription ... Mus musculus Mus musculus
Cell Cardiac (Gata4S105A ...
Perturbation Phenylephrine
Disease Cardiac Hypertrophy
20 Cardiomyocyte response to biomechanical ... Rattus norvegicus Rattus norvegicus
Cell Cardiomyocyte
Perturbation Phenylephrine
Disease Mechanical Stress
21 Fluoxetine effect on the hippocampus Mus musculus Mus musculus
Cell Hippocampus
Perturbation Fluoxetine
Disease Depression
22 Antipsychotic agent olanzapine effect on the ... Rattus norvegicus Rattus norvegicus
Cell Brain frontal cortices
Perturbation Olanzapine
Disease Schizophrenia
23 Antipsychotic agents clozapine and haloperidol ... Mus musculus Mus musculus
Cell Brain
Perturbation Clozapine
Disease Psychosis
24 Antipsychotic agents clozapine and haloperidol ... Mus musculus Mus musculus
Cell Brain
Perturbation Haloperidol
Disease Psychosis
25 Catecholamine stress effect on hearts of beta2 ... Mus musculus Mus musculus
Cell Cardiac (Wildtype FVB)
Perturbation Isoproterenol
Disease Catecholamine Stress
26 Catecholamine stress effect on hearts of beta2 ... Mus musculus Mus musculus
Cell Cardiac (Wildtype ...
Perturbation Isoproterenol
Disease Catecholamine Stress
27 Catecholamine stress effect on hearts of beta2 ... Mus musculus Mus musculus
Cell Cardiac (Wildtype ...
Perturbation Isoproterenol
Disease Catecholamine Stress
28 Catecholamine stress effect on hearts of beta2 ... Mus musculus Mus musculus
Cell Cardiac (Wildtype ...
Perturbation Isoproterenol
Disease Catecholamine Stress
29 In vitro pineal gland organ culture response ... Rattus norvegicus Rattus norvegicus
Cell Pineal (Brain)
Perturbation Norepinephrine
30 Isoproterenol-induced cardiomyopathy and ... Mus musculus Mus musculus
Cell Cardiac
Perturbation Isoproterenol
Disease Cardiac Disease
31 Identical twins discordant for Multiple ... Homo sapiens Homo sapiens
Gene KLRB1
Cell Lymphocytes (CD8+ T ...
Disease Multiple Sclerosis
32 Identical twins discordant for Multiple ... Homo sapiens Homo sapiens
Gene KLRB1
Cell Lymphocytes (CD4+ T ...
Disease Multiple Sclerosis
33 Effect of estrogen receptor- or retinoic acid ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer Cell
Perturbation Estrogen depletion ...
Disease Breast Cancer
34 Effect of estrogen receptor- or retinoic acid ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer Cell
Perturbation Retinoic acid ...
Disease Breast Cancer
35 Effect of estrogen receptor- or retinoic acid ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer Cell
Perturbation Estrogen receptor ...
Disease Breast Cancer
36 Effect of estrogen receptor- or retinoic acid ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer Cell
Perturbation Estrogen receptor ...
Disease Breast Cancer
37 Effect of estrogen receptor- or retinoic acid ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer Cell
Perturbation Retinoic acid ...
Disease Breast Cancer
38 Effect of estrogen receptor- or retinoic acid ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer Cell
Perturbation Retinoic acid ...
Disease Breast Cancer
39 Embryonic stem cell response to STAT3 ... Mus musculus Mus musculus
Gene STAT3
Cell Embryonic Stem Cell
Perturbation Gene Overexpression
Disease Pluripotency Maintainence
40 Dopamine β-hydroxylase knockout effect on ... Mus musculus Mus musculus
Cell Cardiac
Perturbation Adrenergic hormone ...
Disease Heart Failure
41 Expression data from Hes1 conditional ... Mus musculus Mus musculus
Gene HES1
Cell Bone Marrow
Perturbation Knockout
Disease Leukemia
42 Expression data from PKM1 or PKM2 expressing ... Mus musculus Mus musculus
Gene PKM2
Cell Mouse Embryonic ...
Perturbation Deletion; Tamoxifen
Disease Global Gene Expression
43 Gene expression data from type II pneumocytes ... Mus musculus Mus musculus
Gene TERF2
Cell Alveolar Epithelial ...
Perturbation Deletion
Disease Degenerative Disease
44 HOXB7 is an ERα cofactor in the activation of ... Homo sapiens Homo sapiens
Gene ERBB2
Cell MCF7 Breast Cancer
Perturbation Overexpression of HOXB7
Disease Breast Cancer
45 Knock out of NOTCH1-bound MYC enhancer (N-Me) Mus musculus Mus musculus
Gene NOTCH1
Cell Lymphoblastic ...
Perturbation Knockout
Disease Cancer
46 MicroRNAs control the apoptotic threshold in ... Mus musculus Mus musculus
Cell Stem Cell
Perturbation Tamoxifen
Disease Cell Apoptosis
47 Expression data from embryonic stem cells ... Mus musculus Mus musculus
Gene FOXD3
Cell Embryonic Stem Cells
Perturbation Overexpression
Disease Pluripotency and ...
48 Expression data from embryonic stem cells ... Mus musculus Mus musculus
Gene NFATC3
Cell Embryonic Stem Cells
Perturbation Overexpression
Disease Pluripotency and ...
49 Expression data from embryonic stem cells ... Mus musculus Mus musculus
Gene NFATC3
Cell Embryonic Stem Cells
Perturbation Overexpression of ...
Disease Pluripotency and ...
50 Expression data from embryonic stem cells ... Mus musculus Mus musculus
Gene FOXD3
Cell Embryonic Stem Cells
Perturbation Knockout
Disease Pluripotency and ...
51 Expression data from embryonic stem cells ... Mus musculus Mus musculus
Gene FOXD3
Cell Embryonic Stem Cells
Perturbation FOXD3 Conditional ...
Disease Pluripotency and ...
52 Calcineurin-dependent transcriptome in ICN1 ... Mus musculus Mus musculus
Cell Lymphoblastic ...
Perturbation Tamoxifen
Disease Cancer
53 Transgenic model of selective ATF6 activation: ... Mus musculus Mus musculus
Cell Cardiac ATF6MER ...
Perturbation Tamoxifen
Disease Endoplasmic Reticulum ...
54 Transgenic model of selective ATF6 activation: ... Mus musculus Mus musculus
Cell Cardiac ATF6MER ...
Perturbation Tamoxifen
Disease Endoplasmic Reticulum ...
55 Genes regulated by estrogen and ... Homo sapiens Homo sapiens
Cell MCF7 Breast Cancer
Perturbation Tamoxifen
Disease Breast Cancer`
56 Expression data from chemically-induced skin ... Mus musculus Mus musculus
Gene SOX2
Cell Cancer Stem Cell
Perturbation Knockin
Disease Cancer
57 Expression data from adult lungs isolated from ... Mus musculus Mus musculus
Cell Lung
Perturbation Tamoxifen
Disease Hemorrhagic ...
58 Effect of genetic Zfx deletion on gene ... Mus musculus Mus musculus
Cell Lymphoblastic ...
Perturbation Tamoxifen
Disease Leukemia
59 Identification of Sox9-Regulated Pathways ... Mus musculus Mus musculus
Gene SOX9
Cell Pancreas (Epithelial)
Perturbation Knockdown
60 Murine forestomach epithelial sheets: Controls ... Mus musculus Mus musculus
Gene SOX9
Cell Forestomach (Epithelial)
Perturbation Overexpression
Disease Transcriptional Profiling
61 Tamoxifen effect on SRC-1-deficient ... Homo sapiens Homo sapiens
Gene NCOA1
Cell Breast Cancer
Perturbation Tamoxifen
Disease Breast Cancer
62 Expression data from MCF7 tumor xenografts ... Homo sapiens Homo sapiens
Cell Breast Cancer
Perturbation Tamoxifen
Disease Breast Cancer
63 mRNA expression data from mice infected with ... Mus musculus Mus musculus
Cell gastric tissue
Perturbation Tamoxifen
Disease H. Pylori
64 Effect of estrogen receptor- or retinoic acid ... Homo sapiens Homo sapiens
Cell Breast Cancer
Perturbation Tamoxifen (100nM)
Disease Breast Cancer
65 Effect of estrogen receptor- or retinoic acid ... Homo sapiens Homo sapiens
Cell Breast Cancer
Perturbation Tamoxifen (500nM)
Disease Breast Cancer
66 Tamoxifen-resistant breast cancer cell line ... Homo sapiens Homo sapiens
Cell MCF7 -B7 Tamoxifen ...
Perturbation Tamoxifen
Disease Breast Cancer
67 Tamoxifen-resistant breast cancer cell line ... Homo sapiens Homo sapiens
Cell MCF7 -G11 Tamoxifen ...
Perturbation Tamoxifen
Disease Breast Cancer
68 Expression profiling in control and YY1 ... Mus musculus Mus musculus
Gene YY1
Cell Intestinal Stem cell
Perturbation Tamoxifeninduced Knockout
Disease Intestinal Disease; ...
69 Heart tissue from Nelf-b CreER mice Mus musculus Mus musculus
Gene NELF
Cell Heart Tissue
Perturbation Tamoxifeninduced Knockout
Disease Cardiac Stress
70 Expression data during plantaris muscle ... Mus musculus Mus musculus
Cell Plantaris Muscle
Perturbation Tamoxifen
Disease Muscle Hypertrophy
71 Effect of genetic Zfx deletion on gene ... Mus musculus Mus musculus
Cell Acute Myeloid ...
Perturbation Tamoxifen
Disease Leukemia
72 Effect of genetic Zfx deletion on gene ... Mus musculus Mus musculus
Cell Acute Myeloid ...
Perturbation Tamoxifen
Disease Leukemia
73 Estrogen receptor dynamics in diverse ... Homo sapiens Homo sapiens
Cell Breast Cancer
Perturbation Tamoxifen
Disease Breast Cancer
74 Expression data from MCF7 wt xenografts Homo sapiens Homo sapiens
Cell Breast Cancer
Perturbation Tamoxifen + Gefinitinib
Disease Breast Cancer
75 Comparison of Hepatocyte nuclear factor 4 ... Mus musculus Mus musculus
Cell Hepatocyte (HNF4alpha ...
Perturbation Tamoxifen
Disease Carcinoma
76 Comparison of Hepatocyte nuclear factor 4 ... Mus musculus Mus musculus
Cell Hepatocyte ...
Perturbation Tamoxifen
Disease Carcinoma
77 Tlx (nr2e1)-dependent gene expression in adult ... Mus musculus Mus musculus
Cell Neural Stem Cell
Perturbation Tamoxifen (36hr)
Disease Global Gene ...
78 KMT1E Mediated H3K9 Methylation Is Required ... Mus musculus Mus musculus
Cell ES cells (Setdb1 ...
Perturbation Tamoxifen
Disease ES cell propagation
79 Expression data from tamoxifen treated and ... Mus musculus Mus musculus
Cell Heart (alphaMHCMerCreMer)
Perturbation Tamoxifen (40mg/kg; 1 ...
Disease CardioMyopathy
80 Expression data from tamoxifen treated and ... Mus musculus Mus musculus
Cell Heart (alphaMHCMerCreMer)
Perturbation Tamoxifen (40mg/kg; 4 ...
Disease CardioMyopathy
81 Expression data from tamoxifen treated and ... Mus musculus Mus musculus
Cell Heart (Wildtype)
Perturbation Tamoxifen (40mg/kg; 4 ...
Disease CardioMyopathy
82 Expression data from primary MEF lacking ... Mus musculus Mus musculus
Gene HDAC1
Cell Mouse Embryonic ...
Perturbation Tamoxifen
Disease MEF transcription ...
83 Expression data from primary MEF lacking ... Mus musculus Mus musculus
Gene HDAC1
Cell Mouse Embryonic ...
Perturbation Tamoxifen ...
Disease MEF transcription ...
84 Tlx (nr2e1)-dependent gene expression in adult ... Mus musculus Mus musculus
Cell Neural Stem Cell ...
Perturbation Tamoxifen (36hr)
Disease Tlx-regulated gene ...
85 Tlx (nr2e1)-dependent gene expression in adult ... Mus musculus Mus musculus
Cell Neural Stem Cell ...
Perturbation Tamoxifen (60hr)
Disease Tlx-regulated gene ...
86 Tlx (nr2e1)-dependent gene expression in adult ... Mus musculus Mus musculus
Cell Neural Stem Cell ...
Perturbation Tamoxifen (36hr)
Disease Tlx-regulated gene ...
87 Tlx (nr2e1)-dependent gene expression in adult ... Mus musculus Mus musculus
Cell Neural Stem Cell ...
Perturbation Tamoxifen (60hr)
Disease Tlx-regulated gene ...
88 Microarray profiling of rats treated for 21 ... Rattus norvegicus Rattus norvegicus
Cell Frontal Cortex
Perturbation Haloperidol ...
Disease Gene expression ...
89 Microarray profiling of rats treated for 21 ... Rattus norvegicus Rattus norvegicus
Cell Frontal Cortex
Perturbation Risperidone (5mg/kg/d ...
Disease Gene expression ...
90 Microarray profiling of rats treated for 21 ... Rattus norvegicus Rattus norvegicus
Cell Hippocampus
Perturbation Haloperidol ...
Disease Gene expression ...
91 Microarray profiling of rats treated for 21 ... Rattus norvegicus Rattus norvegicus
Cell Hippocampus
Perturbation Risperidone (5mg/kg/d ...
Disease Gene expression ...
92 Microarray profiling of rats treated for 21 ... Rattus norvegicus Rattus norvegicus
Cell Striatum
Perturbation Haloperidol ...
Disease Gene expression ...
93 Microarray profiling of rats treated for 21 ... Rattus norvegicus Rattus norvegicus
Cell Striatum
Perturbation Risperidone (5mg/kg/d ...
Disease Gene expression ...
94 Hippocampus_Lithium Chloride (02%, 21 ... Rattus norvegicus Rattus norvegicus
Cell Hippocampus
Perturbation Lithium Chloride ...
Disease Gene expression ...
95 Frontal Cortex_Lithium Chloride (02%, 21 ... Rattus norvegicus Rattus norvegicus
Cell Frontal Cortex
Perturbation Lithium Chloride ...
Disease Gene expression ...
96 Striatum_Lithium Chloride (02%, 21 days)_Gene ... Rattus norvegicus Rattus norvegicus
Cell Striatum
Perturbation Lithium Chloride ...
Disease Gene expression ...
97 Peripheral Blood_Lithium _Bipolar Disorder Homo sapiens Homo sapiens
Cell Peripheral Blood
Perturbation Lithium
Disease Bipolar Disorder
98 Peripheral Blood_Lithium (baseline)_Bipolar ... Homo sapiens Homo sapiens
Cell Peripheral Blood
Perturbation Lithium (baseline)
Disease Bipolar Disorder
99 Peripheral Blood_Lithium (1 month)_Bipolar ... Homo sapiens Homo sapiens
Cell Peripheral Blood
Perturbation Lithium (1 month)
Disease Bipolar Disorder
100 Antipsychotic agents clozapine and haloperidol ... Mus musculus Mus musculus
Cell Right forebrain
Perturbation Haloperidol (4 weeks ...
Disease Agranulocytosis, ...
101 Antipsychotic agents clozapine and haloperidol ... Mus musculus Mus musculus
Cell Right forebrain
Perturbation Clozapine (4 weeks of ...
Disease Agranulocytosis, ...