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| Title / Description | Embryonic stem cell response to STAT3 overexpression in vitro (MG-U74A) |
| Accession | GDS3444 |
| Summary | Analysis of cultured embryonic stem (ES) cells overexpressing the transcription factor STAT3. STAT3 is a downstream target of the LIF signaling cascade. LIF activation maintains ES cells in a pluripotent state. Results provide insight into the role of STAT3 in maintenance of ES cell pluripotency. |
| Organism | Mus musculus |
| Platform | GPL81 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Gene | STAT3 |
| Cell | Embryonic Stem Cell |
| Perturbation | Gene Overexpression |
| Disease | Pluripotency Maintainence |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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