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| Title / Description | Tamoxifen-resistant breast cancer cell line MCF7 subclones |
| Accession | GDS4051 |
| Summary | Analysis of tamoxifen-sensitive and -resistant subclones of breast tumor MCF7 cells treated with estrogen (E), 4-hydroxy-tamoxifen (4-OHT), or E + 4-OHT. Success of 4-OHT therapy is limited by intrinsic and acquired drug resistance. Results provide insight into mechanisms leading to drug resistance. |
| Organism | Homo sapiens |
| Platform | GPL570 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell | MCF7 Breast Tumor Cell (Tamoxifen Sensitive) |
| Perturbation | Tamoxifen |
| Disease | Breast Cancer |
| Principal Component Analysis | |
| Hierarchical clustering |
| Gene lists | Enrichr | L1000CDS2 | PAEA | |
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