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| Title / Description | Anti-IL-17 monclonal antibody ixekizumab effect on chronic psoriasis |
| Accession | GDS4458 |
| Summary | Analysis of psoriatic skin biopsies from patients treated with 150mg of subcutaneous anti-IL-17 mAb ixekizumab (previously LY2439821) at weeks 0 and 2. IL-17 blockade resulted in a high-grade clinical improvement in psoriasis. Results provide insight into the role of IL-17 in disease pathogenesis. |
| Organism | Homo sapiens |
| Platform | GPL571 |
| Normalized | False |
| Parsed SOFT file |
| Differential expression method | Characteristic Direction |
| Cutoff | 500 |
| Cell_type | Skin |
| Drug_id | DB11569 |
| Drug_name | Ixekizumab - 150mg |
| Organism | Human |
| Gene lists | Enrichr | L1000CDS2 | PAEA | Crowdsourcing | |
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